Colaborações / Publications (Collaborations)

Neste item colocamos a lista dos artigos científicos publicados em quais o coordenador do laboratório (Prof. Eduardo), e membros deste laboratório, colaboraram cientificamente e assinam como coautores.

In this item, it is presented the list of published scientific papers in which the principal investigator (Prof. Eduardo), and members of this laboratory, collaborated scientifically and signed as co-authors.


de Oliveira J, Engel DF, de Paula GC, Dos Santos DB, Lopes JB, Farina M, Moreira ELG, de Bem AF. High Cholesterol Diet Exacerbates Blood-Brain Barrier Disruption in LDLr-/- Mice: Impact on Cognitive Function. J Alzheimers Dis. 2020;78(1):97-115. doi: 10.3233/JAD-200541.


Batschauer T, Cordeiro JM, Simas BB, Brunetta HS, Souza RM, Nunes EA, Reis WL, Moreira ELG, Crestani CC, Santos ARS, Speretta GFF. Behavioral, cardiovascular and endocrine alterations induced by chronic stress in rats fed a high-fat diet. Physiol Behav. 2020. 223:113013. doi: 10.1016/j.physbeh.2020.113013.


Santos DB, Colle D, Moreira ELG, Santos AA, Hort MA, Santos K, Oses JP, Razzera G, Farina M. Probucol Protects Neuronal Cells Against Peroxide-Induced Damage and Directly Activates Glutathione Peroxidase-1. Mol Neurobiol. 2020 57(8):3245-3257. doi: 10.1007/s12035-020-01963-w.


De Paula GC, de Oliveira J, Engel DF, Lopes SC, Moreira ELG, Figueiredo CP, Prediger RD, Fabro de Bem A. Red wine consumption mitigates the cognitive impairments in low-density lipoprotein receptor knockout (LDLr-/-) mice. Nutr Neurosci. 2020 Jan 7:1-11. doi: 10.1080/1028415X.2019.1704472. [Epub ahead of print]


de Oliveira J, Engel DF, de Paula GC, Melo HM, Lopes SC, Ribeiro CT, Delanogare E, Moreira JCF, Gelain DP, Prediger RD, Gabilan NH, Moreira ELG, Ferreira ST, de Bem AF. LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis. J Alzheimers Dis. 2020;73(2):585-596. doi: 10.3233/JAD-190742.


Prediger RD, Schamne MG, Sampaio TB, Moreira ELG, Rial D. Animal models of olfactory dysfunction in neurodegenerative diseases. Handb Clin Neurol. 2019;164:431-452. doi: 10.1016/B978-0-444-63855-7.00024-1.


Gomes FA, Flores RA, Bruxel MA, da Silva FN, Moreira ELG, Zoccal DB, Prediger RD, Rafacho A. Glucose homeostasis is not affected in a murine model of Parkinson’s disease induced by 6-OHDA. Front Neurosci. 2019 Jan 9;12:1020. doi: 10.3389/fnins.2018.01020.


De Oliveira PA, Bem J, Matheus FC, Schwarzbold ML, Moreira EL, Rial D, Walz R, Prediger RD. Moderate traumatic brain injury increases the vulnerability to neurotoxicity induced by systemic administration of 6- hydroxydopamine in mice. Brain Research, 1663, 78-86, 2017.


Santos DB, Colle D, Moreira EL, Hort MA, Godoi M, Le Douaron G, Braga AL, Assreuy J, Mjchel PP, Prediger RD, Raisman-Vozari R, Farina M. Succinobucol, a Non-Statin Hypocholesterolemic Drug, Prevents Premotor Symptoms and Nigrostriatal Neurodegeneration in an Experimental Model of Parkinson?s Disease. Molecular Neurobiology, 54, 1513-30, 2017.


Dos Santos AA., Naime AA., de Oliveira J., Colle D., dos Santos DB., Hort MA., Moreira EL., Sunol C., de Bem AF., Farina M. Long-term and lowdose malathion exposure causes cognitive impairment in adult mice: evidence of hipocampal mitochondrial dysfunction, astrogliosis and apoptotic events. Archives of Toxicology. 90, 647-60, 2016.


Szczepanik JC, de Oliveira PA, de Oliveira J, Mack JM, Engel DF, Rial D, Moreira EL, de Bem AF, Prediger RD. Caffeine Mitigates the Locomotor Hyperactivity in Middle-aged Low-density Lipoprotein Receptor (LDLr)-Knockout Mice. CNS Neuroscience & Therapeutics, 22, 420-22, 2016.


Engel DF, de Oliveira J, Lopes JB, Santos DB, Moreira EL, Farina M, Rodigues AL, Brocardo PS, de Bem AF. Is there an association between hypercholesterolemia and depression? Behavioral evidence from the LDLr−/− mouse experimental model. Behavioural Brain Research, 311, 31-8, 2016.


Lopes JB, de Oliveira J, Engel DF, de Paula GC, Moreira EL, de Bem AF. Efficacy of Donepezil for Cognitive Impairments in Familial Hypercholesterolemia: Preclinical Proof of Concept. CNS Neuroscience & Therapeutics, 21, 964-66, 2015.


Vecchia DD, Schamne MG, Ferro MM, Santos AFC, Latyki CL, Lara, DV, Bem J, Moreira EL, Prediger RD, Miyoshi E. Effects of Hypericum perforatum on turning behavior in an animal model of Parkinson’s disease. Brazilian Journal of Pharmaceutical Sciences, 51, 111-15, 2015.


Lindner RG., Santos DB., Colle D, Moreira EL., Prediger RD., Farina M., Khalin NM., Mainardes MR. Improved neuroprotective effects of resveratol-loades polysorbate 80-coated poly(lactide) nanoparticles in MPTP-induced parkinsonism. Nanomedicine, v.10(7), p.1127-38, 2015.


Santos DB., Colle D., Moreira EL., Peres KC., Ribeiro RP., dos Santos AA., de Oliveira J., Hort MA., de Bem AF., Farina M. Probucol mitigates streptozotocin-induced cognitive and biochemical changes in mice. Neuroscience. v.284, p. 590-600, 2015.


de Oliveira J., Moreira EL., Santos DB., Piermartiri TC., Dutra RC., Pinton S., Tasca CI., Farina M., Prediger RD., Bem AF. Increased susceptibilitty to amyloid-β-induced neurotoxicity in mice lacking the low-density lipoprotein receptor. Journal of Alzheimer’s Disease. v.41, p. 43-60, 2014.


Rial D., Pamplona FA., Moreira EL., Moreira KM., Hipolide D., Rodrigues DI., Dombrowski PA., da Cunha C., Agostinho P., Takahashi RN., Walz R., Cunha RA., Prediger RD. Cellular príon protein is presente in dopaminergic neurons and modulates the dopaminergic system. European Journal of Neuroscience. v. 40, p. 2479-2486, 2014.


Mancini G., de Oliveira J., Hort MA., Moreira EL., Ribeiro-do-Valee RM., Rocha JB., de Bem AF. Diphenyl diselenide differently modulates cardiovascular redox responses in Young and adult middle-aged LDLr- /- hypercholesterolemic mice. Journal of Pharmacy and Pharmacology. v. 66, p. 387-397, 2013.


De Oliveira J., Moreira EL., Mancini G., Hort MA., Latini A., Ribeiro-doValle RM., Farina M., Da Rocha JBT., De Bem AF. Diphenyl Diselenide Prevents Cortico-cerebral Mitochondrial Dysfunction and Oxidative Stress Induced by Hypercholesterolemia in LDL Receptor Knockout Mice. Neurochemical Research. v. 38, p.2028-36, 2013.


Aguiar AS., Tristão FSM., Amar M., Chevarin C., Glaser V., Paula Martins R., Moreira EL., Mongeau R., Lanfumey L., Raisman-Vozari R., Latini A., Prediger RD. Six Weeks of Voluntary Exercise don´t Protect C57BL/6 Mice Against Neurotoxicity of MPTP and MPP+. Neurotoxicity Research, v. 25, p.147-52, 2013.


Dutra RC., Moreira EL., Alberti TB., Marcon R., Prediger RD., Calixto JB. Spatial reference memory deficits precede motor dysfunction in an experimental autoimmune encephalomyelitis model: the role of kallikrein-kinin system. Brain, Behavior, and Immunity. V. 33, p. 90- 101, 2013.


Aguiar AS., Moreira EL., Hoeller AA., Oliveira PA., Córdova FM., Glaser V., Walz R., Cunha RA., Leal RB., Latini A., Prediger RD. Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopaminelesioned mice. Neuroscience. , v.243, p.46 – 53, 2013.


Colle D., Santos DB., Moreira EL., Hartwig JM., dos Santos AA., Zimmermann LT., Hort MA., Farina M. Probucol Increases Striatal Glutathione Peroxidase Activity and Protects against 3-Nitropropionic Acid-Induced Pro-Oxidative Damage in Rats. Plos One. v.8, p.e67658, 2013.


Ribeiro RP., Moreira EL., Santos DB., Colle D., Santos AA., Peres KC., Figueiredo CP., Farina M. Probucol Affords Neuroprotection in a 6- OHDA Mouse Model of Parkinson’s Disease. Neurochemical Research. v.38, p.660 – 668, 2013.


Aguiar A., Castro AA., Moreira EL., Glaser V., Santos ARS., Tasca CI., Latini A., Prediger RD. Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling. Mechanisms of Ageing and Development (Print). v.132, p.560 – 567, 2011.


Santos DB, Peres KC., Ribeiro RP., Colle D, dos Santos, AA., Moreira EL., Souza D., Figueiredo CP., Farina, M. Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid –β peptide in mice. Experimental Neurology. v.233, p.767 – 775, 2012.


de Oliveira J., Hort MA., Moreira EL, Glaser V., Ribeiro-do-Valle RM., Prediger RD., Farina M., Latini A., Bem AF. Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress. Neuroscience. v.197, p.99 – 106, 2011.


Prediger RD., Aguiar A., Moreira EL., Matheus FC., Castro AA., Walz R., Bem, AF., Latini AS., Tasca CI., Farina M., Raisman-Vozari R. The Intranasal Administration of 1-Methyl-4-Phenyl-1,2,3,6- Tetrahydropyridine (MPTP): A New Rodent Model to Test Palliative and Neuroprotective Agents for Parkinson’s disease. Current Pharmaceutical Design (Print). v.17, p.489 – 507, 2011.


Figueiredo CP., Antunes VL., Moreira EL., de Mello N., Medeiros R., Di Giunta G., Lobão-Soares B., Linhares M., Lin K., Mazzuco TL., Prediger RD., Walz, R. Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus. Peptides (New York, N.Y. 1980). v.32, p.781 – 789, 2011.


DalBó S., Moreira ELG., Brandão FC., Horst H., Pizzolatti MG., Micke GA., Ribeiro-do-Valle, RM. Mechanisms Underlying the Vasorelaxant Effect Induced by Proanthocyanidin-Rich Fraction From Croton celtidifolius in Rat Small Resistance Arteries. Journal of Pharmacological Sciences. v.106, p.234 – 241, 2008.